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Thorne

5-MTHF

5-MTHF is a bioactive, methylated form of folate, an essential B vitamin that supports heart, brain, blood, and bone health and is suitable for individuals with MTFHR gene mutations.

Strength
$19.20$24.00save $4.80

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Practitioner grade
Direct from the manufacturer
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These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Product insights

  • 5-MTHF is the most bioactive form of folate, ensuring optimal utilization in the body, especially for individuals with MTHFR gene variations.
  • Folate, as 5-MTHF, plays a crucial role in the methylation cycle, influencing various biochemical reactions essential for overall health.
  • 5-MTHF supports the production of key neurotransmitters like serotonin and dopamine, which are vital for mood regulation and cognitive function.
  • By promoting a healthy methylation cycle, 5-MTHF contributes to maintaining normal homocysteine levels, thereby supporting cardiovascular and neurological health.

Suggested use

From the manufacturer
Take 1 capsule one to three times daily or as recommended by a health-care practitioner.

What it supports

5 benefits
  • Supports healthy neurotransmitter production for balanced mood
  • Promotes cardiovascular health by maintaining homocysteine levels
  • Supports healthy fetal development during pregnancy
  • Promotes healthy blood and nerve cell function
  • Supports optimal methylation for overall well-being

What's in it

Per serving
Ingredient
Amount
% Daily Value
Folate (1 mg as L-5-Methyltetrahydrofolate)
1.7 mg DFE
**
Other ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
** Daily Value not established.

The research

2 cited studies
1.
MTHFR Polymorphisms and Folate Metabolism

Research indicates that individuals with MTHFR gene mutations may benefit from 5-MTHF supplementation due to its direct utilization in the folate cycle, bypassing the need for enzymatic conversion.

2.
Folate and Neurotransmitter Synthesis

Studies have demonstrated the importance of folate in the synthesis of neurotransmitters such as serotonin, dopamine, and norepinephrine, highlighting its role in mood regulation and cognitive function.