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Propranolol

Propranolol

Slow down your heart rate and say goodbye to palpitations with propranolol, an FDA-approved beta-blocker designed to improve symptoms of dysautonomia, POTS, Long COVID, and ME/CFS.

ME/CFSLong COVIDPOTS
PEMShortness of BreathHeadachesChest PainPalpitationsSleepDizzinessOrthostatic Intolerance
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Pricing Example

RTHM Safety Assessment

Only charged if approved

$59

Pharmacy Cost

90-day supply + shipping

$11

Total for 90 days

With RTHM discount

$70

RTHM Safety
Assessment Fee

Paid every 90 days
(only charged if approved)

$59

Pharmacy
Cost

90-day supply + shipping, paid to the pharmacy

$11

Estimated total
for 90 days

With RTHM discount

$70

Reduce dizziness fatigue and brain fog

Propranolol helps stabilize and reduce your heart rate, alleviating symptoms like dizziness, fatigue, and cognitive impairment caused by orthostatic intolerance.

Reduce tachycardia

Low-dose propranolol significantly reduces heart palpitations and shakiness in patients with POTS, allowing you to feel calmer and more in control.

Improve exercise tolerance

Propranolol improves exercise tolerance by allowing better heart rate control. Studies show it correlates with improved VO2 max, helping you expand your energy envelope.

Is Propranolol right for me?

Propranolol can help manage:

  • Tachycardia (fast heart rate)
  • Heart palpitations
  • Dizziness and lightheadedness
  • Exercise intolerance
  • Orthostatic intolerance
  • Fatigue
  • Brain fog
  • Chest discomfort

Patients experiencing these symptoms due to Long COVID, ME/CFS, POTS, or dysautonomia may benefit from propranolol.

Propranolol is generally safe and well-tolerated, but side effects can occur, including:

  • Headaches
  • Fatigue
  • Restlessness
  • Dizziness or weakness
  • Nausea or vomiting

More severe side effects may include:

  • Chest tightness
  • Difficulty breathing
  • Worsening chest pain
  • Very slow heartbeat

Propranolol is not recommended for patients with:

  • Severe respiratory conditions (e.g., asthma)
  • Severe bradycardia (very low heart rate)
  • Heart block or congestive heart failure
  • Depression or thyroid disorders

Doses of propranolol through RTHM begin at the very low dose of 2.5mg. If well-tolerated, this amount will increase weekly until the desired therapeutic effect is achieved. You must maintain a detailed log of your heart rate, blood pressure, and symptoms to help your provider find the right dose for you.

What Does the Research Say?

Propranolol significantly reduced heart rate and improved symptoms of orthostatic intolerance, helping patients stabilize while upright.

"Propranolol decreases tachycardia and improves symptoms in the Postural Tachycardia Syndrome (POTS): Less is More" PMID: 19687359

A clinical study in 11 patients found propranolol improved exercise tolerance and VO2 max in POTS patients by controlling heart rate during physical activity.

"Low-dose propranolol and exercise capacity in postural tachycardia syndrome" PMID: 23616163

A clinical study showed orthostatic intolerance (OI) symptoms of POTS patients significantly decreased after 1 month of treatments with propranolol, with continued symptom improvement through month 3. The study also showed improvements in quality of life and depression symptoms.

"Efficacy of Propranolol, Bisoprolol, and Pyridostigmine for Postural Tachycardia Syndrome: a Randomized Clinical Trial"

Research Studies

Propranolol significantly reduced heart rate and improved symptoms of orthostatic intolerance, helping patients stabilize while upright.

"Propranolol decreases tachycardia and improves symptoms in the Postural Tachycardia Syndrome (POTS): Less is More. PMID: 19687359"

View Study

A clinical study in 11 patients found propranolol improved exercise tolerance and VO2 max in POTS patients by controlling heart rate during physical activity.

"Low-dose propranolol and exercise capacity in postural tachycardia syndrome. PMID: 23616163"

View Study

A clinical study showed orthostatic intolerance (OI) symptoms of POTS patients significantly decreased after 1 month of treatments with propranolol, with continued symptom improvement through month 3. The study also showed improvements in quality of life and depression symptoms.

"Efficacy of Propranolol, Bisoprolol, and Pyridostigmine for Postural Tachycardia Syndrome: a Randomized Clinical Trial"

View Study

What People Are Saying About Propranolol

"I've been on propranolol for about two+ weeks now, and the difference is insane to me. I can stand and walk around and barely feel a thing. I cooked three meals in a single weekend when I hadn't been able to cook in over a year. I'm able to take the dog out without getting lightheaded and short of b..."

u/krobie77reddit.com

"saw my cardiologist the other day and i was prescribed propranolol for POTS and yesterday was the first day i took it and as i was standing up my heart rate was only 85-95 … usually it's anywhere between 110-140 while standing. i'm amazed"

u/tiredmonarchreddit.com

"Propranolol helped me so much. I almost entirely stopped fainting and I can walk around stores etc much more easily, without a cane for dizziness and fatigue that I used to use most of the time. I started out on 10mg twice a day, then 20mg twice a day, now 60mg extended release in the morning.No not..."

u/sgsdukereddit.com

"Propranolol helped me more than anything else for <Long COVID>. Its obliterated my POTS symptoms. However, if i miss a dose its incredibly noticeable"

u/Key_Chart_8624reddit.com

"79% of patients reported at least some improvement while taking propranolol for POTS."

Anonymousstuffthatworks.health