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Metformin

Metformin

Metformin may be used off-label to minimize COVID-19 symptoms and reduce Long COVID risk.

Long COVIDLong COVID PreventionAcute COVID
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Pricing example

RTHM Safety Assessment

Only charged if approved

$49

Pharmacy Cost

14-day supply + shipping

$5

Total for 14 days

With RTHM discount

$54
RTHM Safety Assessment Fee

Paid to RTHM. Every 90 days, only if approved.

$49
Pharmacy cost

14-day fill + shipping

$5
Estimated total for 14 days

With RTHM discount

$54

Key benefits

3 highlights
  1. 01

    Minimize Acute COVID-19 Symptoms

    Metformin offers antiviral properties that help reduce the severity of acute COVID-19 symptoms, lowering viral loads and minimizing complications.

  2. 02

    Inflammation Reduction

    Metformin exhibits anti-inflammatory effects, potentially mitigating systemic inflammation characteristic of acute COVID-19 and Long COVID.

  3. 03

    Reduced Risk of Long COVID

    Research shows that metformin reduces the risk of Long COVID by up to 53% when taken within the first week of infection.

Is Metformin right for me?

4 questions

Metformin has been shown to help with:

  • Minimizing acute COVID-19 symptoms
  • Reducing viral load
  • Preventing Long COVID
  • Reducing inflammation

Patients experiencing acute COVID-19 or at risk of Long COVID may find metformin a safe and effective preventive treatment option.

Research & evidence

3 studies

Study #1: Minimize Acute COVID-19 Symptoms

Metformin demonstrated antiviral properties in a study where participants treated with metformin during acute COVID-19 experienced a fourfold reduction in viral load compared to the placebo group.

Metformin and Antiviral Effects in Acute COVID-19
View Study

Study #2: Inflammation Reduction

Metformin exhibits anti-inflammatory properties that may mitigate systemic inflammation present in acute COVID-19 and Long COVID. These effects could reduce the severity of acute infections and the risk of Long COVID development.

Metformin May Reduce Long COVID in Non-Diabetic Population
View Study

Study #3: Reduced Risk of Long COVID

Data presented at the 2024 Infectious Disease Week Annual Meeting revealed that metformin reduced the risk of Long COVID by 53% when prescribed within the first week of an acute SARS-CoV-2 infection.

Metformin for Long COVID Prevention and Unveiling the potential pleiotropic effects of metformin in treating COVID-19: a comprehensive review
View Study